Fluconazole-Associated Birth Defects: A Comprehensive Review

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Use of oral fluconazole during pregnancy and the risk of birth defects.

BACKGROUND Case reports suggest that long-term, high-dose fluconazole treatment for severe fungal infections during pregnancy causes a pattern of birth defects. It is unclear whether commonly used lower doses increase the risk of specific birth defects. METHODS In a registry-based cohort of liveborn infants in Denmark, we evaluated first-trimester oral fluconazole exposure and the risk of bir...

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ژورنال

عنوان ژورنال: INNOVATIONS in pharmacy

سال: 2014

ISSN: 2155-0417

DOI: 10.24926/iip.v5i2.337